See information below on IBS and this treatment. To create a Treatment Checklist, go to the bottom of the screen and enter your information in the four sections: 1) past or present use, 2) frequency and duration, 3) did this treatment work?, and 4) significant side effects. To see the next treatment either click on the treatment list at the bottom of the screen or click ‘Save and Continue to Next Treatment.’ Click ‘Submit (Done)’ to generate a list to print or email, to discuss with your physician.

Tegaserod

How it works:
Acts on specific serotonin receptors targeting nerves in the intestinal tract. These nerves can sense pain and are responsible for bowel function.
Which symptoms it helps:
Overall symptoms in women with IBS-C, constipation, belly pain.
How long it takes to see a benefit:
1-2 weeks.
Who may benefit:
Women with IBS-C under age 65.
FDA approved:
Women with IBS-C under the age of 65 years.
Dosage:
6 mg twice a day.
Special considerations or risks:
Tegaserod is contraindicated in patients with a history of cardiovascular (MI or angina) or cerebrovascular (stroke or TIA) disease, history of ischemic colitis, history of bowel obstruction, symptomatic gallbladder disease, suspected sphincter of Oddi dysfunction, abdominal adhesions, severe renal impairment, or moderate to severe liver impairment. Monitoring for clinical worsening of depression and emergence of suicidal thoughts, especially during the initial few months of treatment, is required.
Most common side effects:
Headache, abdominal pain.

Recommendation:
ACG suggests tegaserod for IBS-C symptom improvement in women younger than 65 years of age.

Recommendation:
N/A
Quality of Evidence:
N/A
Level of Evidence:
Ø
Past and Present Use Frequency and Duration Did this treatment work? Significant Side Effects
Past Use   Present Use   Yes   No   N/A