See information below on IBS and this treatment. To create a Treatment Checklist, go to the bottom of the screen and enter your information in the four sections: 1) past or present use, 2) frequency and duration, 3) did this treatment work?, and 4) significant side effects. To see the next treatment either click on the treatment list at the bottom of the screen or click ‘Save and Continue to Next Treatment.’ Click ‘Submit (Done)’ to generate a list to print or email, to discuss with your physician.

Polyethylene Glycol (PEG)

How it works:
PEG is an osmotic laxative which causes water to be released into the bowel. PEG softens the stool without interfering with the active absorption of nutrients or electrolytes.
Which symptoms it helps:
Consistency and frequency of bowel movements. Little to no effect on pain or bloating in IBS-C patients.
How long it takes to see a benefit:
It may take 2 to 4 days for the PEG to produce a bowel movement. It works best when used between one and two weeks.
Who may benefit:
IBS-C.
FDA approved:
Constipation.
Dosage:
17 grams daily. The dose is either measured by the dosing cup (or one heaping tablespoonful of powder) or the use of one sachet.
Special considerations or risks:
Animal reproductive studies have not been performed with PEG, and it is not known whether PEG can cause fetal harm when administered to a pregnant woman, or can affect reproductive capacity.
Most common side effects:
Abdominal cramping, diarrhea, bloating and flatulence.

Recommendation:
While ACG does not recommend PEG for abdominal pain and bloating in IBS-C patients, PEG may be helpful for treating chronic constipation.

Recommendation:
LOW
Quality of Evidence:
WEAK
Level of Evidence:
√-
Past and Present Use Frequency and Duration Did this treatment work? Significant Side Effects
Past Use   Present Use   Yes   No   N/A