Antispasmodics - Dicyclomine (Bentyl) and Hyoscyamine (Levsin)
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How it works: They work by relaxing the smooth muscle in the colon, which reduces spastic contractions. |
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Which symptoms does it help: Belly pain. |
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How long it takes to see a benefit: Within 1 day. |
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FDA approved: N/A |
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Dosage: Dicyclomine – 20 mg; hyoscyamine regular release – 0.125 mg to 0.25 mg; hyoscyamine extended release – 0.375 mg to 0.75 mg |
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Special considerations or risks: Cannot be given to those who have a bowel blockage. |
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Most common side effects: Dizziness, drowsiness, blurred vision, nausea, and dry mouth. |
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Recommendation: While ACG suggests that antispasmodics (e.g., hyoscine, dicyclomine) may not be helpful for overall IBS symptoms, their use, in the short term, may help relieve abdominal pain. |
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